FDA is using all available tools at its disposal to ensure that dietary supplements containing the stimulant dimethylamylamine (DMAA) are no longer distributed and available for sale to consumers in the marketplace.

The ingredient is most commonly used in supplements promising weight loss, muscle building and performance enhancement; it can elevate blood pressure and could lead to cardiovascular problems, including heart attack, shortness of breath and tightening of the chest, according to FDA. Given the known biological activity of DMAA, the ingredient may be particularly dangerous when used with caffeine.

As of April 11, FDA had received 86 reports of illnesses and death associated with supplements containing DMAA. The majority are voluntary reports from consumers and healthcare practitioners. The illnesses reported include heart problems and nervous system or psychiatric disorders. However, a report is not proof that the product actually caused the problem.

FDA has warned companies known to be using DMAA in dietary supplements that those products containing this ingredient are illegal. Such warnings offer the quickest way at FDA’s disposal to halt the further distribution of dietary supplements containing DMAA. As FDA continues the process needed to get DMAA off the market, the agency is urging consumers to check labels and avoid any dietary supplements containing DMAA, which is referred to on different product labels by 10 possible names. The alternatives are listed at FDA’s DMAA website.